Phylogenetic relationship and structural organizations among LA-Motif containing proteins
(adapted from Bousquet-Antonelli and Deragon, (2009) RNA; Bayfield et al. (2010) BBA)
La-motif proteins fall into 5 evolutionary conserved families. Members of the same family share conserved domain organization. As for the genuine LA proteins, the LAM-RRM organization is conserved in every LA-Related Protein families. With the exception of the LARP7 family which has a canonical RRM1, other LARP families display a variant RRM named: RRM-L3a/3b; RRM-L4 and RRM-L5. In each family, the most commonly represented domain organization is highlighted (black arrow).
Contact: Jean-Marc DERAGON <jean-marc.deragon@univ-perp.fr>
